He started his service in the Diplomatic Corps of the Holy See in April, 1969, in Cameroon.
He was transferred to the Apostolic Nunciature in Jerusalem on July 19, 1971, and subsequently to the Apostolic Nunciatures in Cuba in 1974, in Algeria in 1978, in Nicaragua in 1979, in Belgium in 1981, and then in India in May, 1984 with the rank of Counselor.
Archbishop Sambi was consecrated as Bishop and made Titular Archbishop of Belcastro on November 9, 1985.
He was nominated Pro-Apostolic Nuncio in Burundi on October 10, 1985, Pro-Apostolic Nuncio in Indonesia on November 28, 1991, and Apostolic Nuncio in Israel and Cyprus, and Apostolic Delegate in Jerusalem and Palestine on June 6, 1998.
Archbishop Sambi speaks Italian, English, French and Spanish. (source: USCCB)